ANEMIA IN WOMEN?
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Re: ANEMIA IN WOMEN?
Who Is At Risk for Thalassemia?
This is from the National Heart and Lung Institute Site on the internet. NHLI is associated with the National Institues of heatlth (http://www.nhlbi.nih.gov/health/dci/Diseases/Thalassemia/Tha...):
Thalassemia is passed from parents to children through their genes.
Thalassemia affects both males and females.
Beta thalassemias affect people of Mediterranean origin or ancestry (Greek, Italian, Middle Eastern) and people of Asian and African descent.
Alpha thalassemias mostly affect people of Southeast Asian, Indian, Chinese, or Filipino origin or ancestry.
Beta Thalassemia
Two genes are involved in making the beta globin part of hemoglobin—one from each parent. Beta thalassemia occurs when one or both of the two genes are variant.
If one gene is affected, a person is a carrier and has mild anemia. This condition is called beta thalassemia trait, or beta thalassemia minor.
If both genes are variant, a person may have moderate anemia (beta thalassemia intermedia, or mild Cooley’s anemia) or severe anemia (beta thalassemia major, or Cooley’s anemia).
Cooley’s anemia, or beta thalassemia major, is a rare condition. A survey in 1993 found 518 Cooley’s anemia patients in the United States. Most of these persons had the severe form of the illness, but there may be more who are not diagnosed.
If two people with beta thalassemia trait (carriers) have a baby, one of three things can happen:
The baby could receive two normal genes (one from each parent) and have normal blood (1 in 4 chance, or 25 percent).
The baby could receive one normal gene from one parent and one variant gene from the other parent and have thalassemia trait (2 in 4 chance, or 50 percent).
The baby could receive two thalassemia genes (one from each parent) and have a moderate to severe form of the disease (1 in 4 chance, or 25 percent).
Vicki Crawford Carroll
This is from the National Heart and Lung Institute Site on the internet. NHLI is associated with the National Institues of heatlth (http://www.nhlbi.nih.gov/health/dci/Diseases/Thalassemia/Tha...):
Thalassemia is passed from parents to children through their genes.
Thalassemia affects both males and females.
Beta thalassemias affect people of Mediterranean origin or ancestry (Greek, Italian, Middle Eastern) and people of Asian and African descent.
Alpha thalassemias mostly affect people of Southeast Asian, Indian, Chinese, or Filipino origin or ancestry.
Beta Thalassemia
Two genes are involved in making the beta globin part of hemoglobin—one from each parent. Beta thalassemia occurs when one or both of the two genes are variant.
If one gene is affected, a person is a carrier and has mild anemia. This condition is called beta thalassemia trait, or beta thalassemia minor.
If both genes are variant, a person may have moderate anemia (beta thalassemia intermedia, or mild Cooley’s anemia) or severe anemia (beta thalassemia major, or Cooley’s anemia).
Cooley’s anemia, or beta thalassemia major, is a rare condition. A survey in 1993 found 518 Cooley’s anemia patients in the United States. Most of these persons had the severe form of the illness, but there may be more who are not diagnosed.
If two people with beta thalassemia trait (carriers) have a baby, one of three things can happen:
The baby could receive two normal genes (one from each parent) and have normal blood (1 in 4 chance, or 25 percent).
The baby could receive one normal gene from one parent and one variant gene from the other parent and have thalassemia trait (2 in 4 chance, or 50 percent).
The baby could receive two thalassemia genes (one from each parent) and have a moderate to severe form of the disease (1 in 4 chance, or 25 percent).
Vicki Crawford Carroll