I wanted to add George's parents - William Wallace Kanouse and Deliah Cullinan married in 1834. There is no Marion Kanouse or anything similar to that name on the 1840 census.
I don't know how else Marion Kanouse could be related to George Kanouse. And, I still can't find any information for Marion Kanouse prior to her marriage to William Miles Humphrey.
Census records show her either born in English Canada (Ontario, I'm guessing) or Ohio. George Kanouse was born in Ottawa, Michigan, so it's possible the Canada indication is really a Canada territory that has the same name as a place in the US. After Marion Kanouse Humphrey's husband died, Marion moved in with her daughter, Ella Humphrey Buckley in Multnomah, Oregon where she died in 1930.
Again, any help would be appreciated!