Hi,
I found your family tree and it looks like you didn't have all of John and Elizabeth's children.
1860 Natchez, Adams, MS
John O'Farrell, b. ireland, 51, merchant
Elizbeth, b. Ireland, 45
Mary, b. MS, 20
John, b. MS, 15
Wm., b. MS, 12
Richard, b. MS, 11
Peter, b. MS, 8
Henry, b. MS, 3
Fannie, b. MS, 2
1870 Natchez, Adams, MS
John J. O'Farrell, b. MS, 24, cotton & corn mills
John O'Farrell Sr., b. Ireland, 60 cotton mills
Eliza, b. Ireland, 55
Francis, dau, b. MS, 15
Henry, b. MS, 11
Evidentally John and Elizabeth died before the 1880 Census. You can do a Google search for Adams County Mississippi Cemeteries and look for them in the inventoried cemeteries.
If you're interested in their will/probate records to establish death dates, you can contact the Adams County Chancery Clerk,
www.adamscountyms.net/chancery-clerk.
You might be able to find more about their life in Ireland at
www.familysearch.org. Successful Searching!