The short answer is, yes, you are a descendant of Conrad Weiser. However, this is not the Conrad Weiser you are thinking of, but his father.

Page 1529 of Weiser Families in America shows Uriah Peter Weiser. His code is RF6218. The line continues back as follows:

RF621 Peter Weiser, 25 May 1789, Tulpehocken Twp., Berks Co. - 18 May 1843, Juniata Co.

RF62 - John Weiser, 23 Jan 1766, Tulpehocken Twp. - 7 Nov 1825, Tulpehocken Twp.

RF6 - Jacob Weiser, 22 Sep 1736, New Jersey - 1 Jan 1808, Tulpehocken Twp.

RF - Christopher Frederick Weiser, 24 Feb 1699, Gross Aspach - 16 Jun 1768, Emmaus, PA.

John Conrad Weiser and wife Anna Magdalena Uebele.

Here is what is listed coming down your line:

RF62183 - William Wesley Weiser.

RF621835 - Clarence William (Charles) Weiser.

The Weiser book has nothing beyond your grandfather.

Pastor Weiser has a copy of the book in loose-leaf form in which he would be happy to enter the more recent information that you could provide.