Stephanie,
I have circumstantial evidence that would lead me to believe that I am a descedent of the same James Twadell of Jennings Co., Indiana, as you apparently are. My connection would be through a possible daughter Elizabeth, born circa 1816. She married Whitson Packer 4 Sep 1834 in McLean Co., Illinois and died 15 May 1865 in Worth Co. Missouri. Do you have any research that would indicate that your James Twadell had a daughter Elizabeth? If so, I would be greatful for the assistance.
Regards,
Paul