Frank Spuches was born in Sicily. He arrived in the US (most likely at New Orleans) in 1887. He married Katherine Tarantino who was born in New Orleans. Her parents were Nicolo Tarantino and Rosa Manfre. Sometime after 1900, Frank Spuches Americanized his name to Frank Spokes.
From what I've found, Spuches is a fairly rare in Sicily, but not unheard of. The name is apparently of Basque origin.
If Frank Spuches followed the naming convention for his children, his parents are most likely Guiseppe and Carmilita.
Any connections?