Mary,
Yes you are correct - it is NEISEN not Niesen. And both of these names can be found in the eastern Wright county area (Albertville/St. Michael & Delano) but I don’t’ believe they are related. My Neisen connection starts with Susanna Weinand who married a M. Neisen and lived in Albertville MN. She died in her early 40's (around 1911) leaving young children. These children lived in Albertville & Monticello area. How are you related?