I know you say you have found your Lyerly ancestors. Good, but Issac Lyerly was not married to Nancy Rex. She married Jacob Menius in 1851. William Rufus is listed as a Rex, 1 year old in 1850. I did not find him in 1860, but in 1870, he is listed with his mother and step-father as Lyerly 21, blacksmith.
Pat Beck