Does this ring a bell for anyone researching the Leed families around Earl/New Holland, Lancaster, PA...
1850 US FEDERAL CENSUS
Isaac Leed (abt 1800)
Jackson Leed (b. 1832)
Margaret Leed (b. 1834)
Mary Leed (b. 1835)
Sahrah Leed (b. 1839)
Anna E Leed (b. 1844)
Emma C Leed (b. 1846)
Eliza A Leed (b. 1847)
From what I can deduce, Isaac's wife died between 1840 and 1850, and Isaac Leed himself died between 1850 and 1860. The 1860 census seems to have the children scattered about Lancaster county as servants, farm laborers, etc. with entirely new families.
I believe Eliza A Leed is the same Eliza A Leed that married James Murray in Upper Darby, PA in 1870 and moved to Wisconsin around 1876.