I too thought that the family came from Richard Lee and Ann Constable but my DNA results put me into the John James Lee of Goochland, VA group. This is a separate Lee line from Richard Lee. From what I understand it's still a mystery as to who's John James' father. The closet relationship beyond John James is to a Henry Lee of York County who came to America around 1630.
Here's a great website for this Lee family.
http://www.jacobhuntertrust.org/wp-content/uploads/2011/06/E... I'm currently working on trying to connect the John James Lee family to my known Lee family in St. Louis. There are just so many Lee's coming and going through Kentucky that it gets a bit crazy.