At the moment I do not know the name of John's first wife, nor exactly how many children they had. However, based on census records, I do know that they had:
James b. about 1841 m. Margaret and Mary, Alonzo, Estella.
Jason b. August 1850 m. Harriet Dennis raised his 1/2 brother Eldridge's daughter Inez May.
I suspect there were others, as John would have been about 40 by the time James was born.