There is a DNA project established to test members of the Isett/Isacks family through Family Tree DNA. Anyone can be tested. You can order a kit from the Family Tree DNA website here:
http://www.familytreedna.com/group-join.aspx?Group=IsettThere are reduced testing rates if you use the link. The administrator is recommending the Y-DNA37 test for the best results. There are testing kits available for females as well.
You can track results at the Isett/Isacks Family DNA website at
http://www.familytreedna.com/public/Isett/default.aspxAt least one kit has already been ordered, so we are waiting for the results and for other samples to compare too. The goal is to find out which Isett lines are actually connected and at what point in history. We also believe the Isacks line connects as well, with just a surname spelling change.
Please consider being tested if you fit in one of these families!