My great grand father was Michael Coen from Galway born about 1842 arrived around 1855-1857 when he was 15. Around 1867 he married Anna Jane Cunningham. They lived not too far from Pittsburgh on the Ohio River - first in Brooke County WV then in Steubenville, Ohio.
Some evidence his parents may have been Patrick and Elisabeth Coen (Cone) but do know he had a stepmother whose biological son's were in Illinois & Indiana in 1905. Anna Cunningham parents were James Cunningham and Susan Barry who arrived from Ireland around 1855. Wonder if these could be related to your Coen raised by Cunningham,