I'm sorry that I cannot be of any help on your Brandons. However, I do want to caution you. Brandon is a very common name. The Brandons of Thyatira Church in Rowan County, North Carolina are not likely connected to the Virginia Brandons. The Rowan County Brandons have been thoroughly researched. My John Brandon (b. 1748 PA, d. 1824 TN) did later (1820s) move to TN. However, he lived in Giles County, TN, not Roane County. He died, and is buried in Giles County TN.
Best of luck on your research.