Email me at
worth@ucla.edu and I will see what I can find out for you.
I found a 1940 census record for Madge and Thomas Irwin and sons Bruce and Thomas in Omaha, Nebraska. Madge lists Iowa for her birth location and Thomas lists Illinois. Also found a Social Security death record for a Thomas Irwin who died in Feb 1963 and got his SS number in Illinois but there is no death location. Do you know - is that him? Do you know where Thomas Irwin died or was buried? (I don't see anything obvious in FindAGrave)
You didn't mention Nebraska before - there were some Bishirs we have researched in Loup Co, NE who had at least one son who moved to Colorado, although the parents of that family were older than Madge by quite a bit, and the male children were much younger.