My Cain line begins with Cornelius and Margaret through Wallace S. Because Mararet was a Sleeth, I assume that the S. in Wallace's middle name is Sleeth.
Wallace is the only child of Cornelius/Margaret that I have a date for: 1814, born in Harrison Co VA. He marriced Dorcas Kerns born 1815 in Hampshire County, VA. Neither of these dates have been verified.
Other children of Cornelius/Margaret are John M, Mary A, Sarah, Alexander, Elizabeth, and James H.
According to "The Descendants of Nicholas Cain" written by Wayne CaIn and Shirley Evan. the Cain's and Sleeth's lived and traveled together. The Sleeth line is also part of my Fitzpatrick lin.
Hope this helps.