The 1900 census for your Louisa Cagley (nee Staples) shows her as born 5/1848 TN. In 1860, in Roane Co, TN there was one Staples family with a Louisa, however, the surname is transcribed as Hopler w/alt of Staples. This Louisa Staples was shown as age 13 b. abt 1847 TN & was the daughter of Abner F Staples age 34 and no wife was in his home.

Siblings were shown as
Jno M age 11
Joseph H age 10
Mary age 8
Katy age 4
Anna age 2
Susannah age 8/12

Since the youngest child is 8 mos old, the mother may have died in childbirth.

Hope this helps!