The first Giessendanner in the Orangeburg Area was Hans Ulrich Giessendanner, the elder, who came to Orangeburg to be a preacher to the German/Swiss settlers in that area.
In general, all Giessendanners from Orangeburg can be traced back to Hans Ulrich or slaves belonging to later generations of Giessendanners.
Hans Ulrich Giessendanner kept a record book of his church, and that record book was continued by his nephew, also Hans Ulrich who took over the church when the elder Giessendanner died. That record book contains much information about the early families of Orangeburg District.
That book of record has been translated, transcribed and expanded on by a gentleman in the Netherlands, Joop Giessendanner. He has a web site that may be of help tracing the Giessendanner family (which Joop also has on the web on a related site.)
Joop's site for the Book of Record is: http://sail.home.xs4all.nl/orange/a-index.html
Joop's Giessendanner family site is:http://sail.home.xs4all.nl/index.html
The other sources for information in Orangeburg County and Calhoun County, South Carolina would be:
Orangeburg County Historical Society
1421 Middleton St
PO Box 1881
Orangeburg, SC 29116-1881
(803) 535-0022 - email@example.com
Calhoun County Museum and Cultural Center
313 Butler Street
St. Matthews, SC 29135
(803) 874-3964 - firstname.lastname@example.org