I happen to have information on John Drew and his wife Anna. Both of John's parents were from Ireland. I am on a search for Frances Caroline Middlebrooks so if you could help me with this that would be very helpful. I don't know about Mary Elizabeth, however I do know about two other children named Rufus and Cora. If that's helpful and on the 1900 Census it says that have had three children but only two of them are living with them so maybe Mary could be already married by this time. I hope this information helps.