Thank you so much for this reply. It seems that yes, it is possible that Isabelle (maiden name unknown) could have been born in Laurel, Kentucky in 1730ish judging from your replies. She married Walter McChesney about 1760's and had 3 children, only one recorded born in 1772 Rockbridge, VA (Borden's Tract) -- their son Walter, Jr.

Where did they marry? When did Walter Sr. come from Northern Ireland (relatives from Armagh, Ulster) arrived in 1770 in VA.

Well, I'm still working on this mystery, but somehow, someway, I will meet someone who has information that can help me.