For what it is worth, that Fayette County marriage bond you mention also had the name William Hooper, as a witness with Hervey Ellis, who was also bondsman.
William Hooper had married Nancy Ellis on 14 Dec 1812 in Fayette County. Their bond only says the parents of Nancy consented, doesn't name them. The witnessing of the later 1820 Smith/Ellis marriage by William Hooper makes it seem likely that Nancy M. Ellis Hooper would have been closely related to Agness C. Ellis Smith.
Later census reports show William Hooper in Fayette County in 1820 and 1830, then in Jefferson County, Kentucky in 1840 and 1850. The widow Nancy M. Hooper remained in Jefferson County in 1860 and probably died there in 1862. These records suggest Nancy M. (Ellis) Hooper was born about 1795 in KY - perhaps this also suggests the Ellis family your seek had arrived in KY before 1800.