I believe Jeremiah brown to be a son of Francis and Barbara (Fitzpatrick) Brown who went to Coles Co. form Highland and Augusta Co's VA. Seton/Seaton is a son of Jeremiah. This has not been documented other than by census records etc. The Johns family next door to Francis Brown in 1850 also had a son Seton. They were friends and from Highland Co, VA too.
Is your Florence a child of Jeremiah? I don't have that material hand at the moment.