If you haven’t already, I suggest you upload your raw data to ftdna and gedmatch. They both have chromosome browsers, which will help you to map specific segments to each of your lines. You also might find additional matches that are more helpful.
If you haven’t expanded your family tree to include siblings of your most distant known ancestors and all of their descendants, also do that. It will help to see how your matches are related. Use the Ancestry databases, familysearch.com, the nli parish registers, and irishgenealogy.ie. The subcription site rootsweb.ie is also helpful and short term subscriptions are relatively inexpensive.
When you get to brick walls using the above resources post inquiries for specific individuals with as much detail as possible.